The Effect of TPP, Theophylline and Theobromine on the Angiogenic Activity of Mononuclear Leukocytes Obtained from Diabetic Patients with Proliferative Retinopathy

Abstract:

Tolpa Peat Preparation (TPP) administered in various doses does not influence the ability of mononuclear cells (MNC) obtained from diabetic patients with proliferative retinopathy to induce the neovascularization response in the H-LIA test. Methylxanthines (theophylline, theobromine) significantly decrease the angiogenic activity of these cells. The therapeutic value of these drugs in proliferative retinopathy should be evaluated.

Authors:

Skopinski, P. et al.

Abbreviated Journal Title: Acta Pol Pharm
Date of Publication: 1993
Journal Volume: 50
Page Numbers: 409 through 411
Country of Publication: Poland
Language of Article: English
Issue/Part/Supplement: 4-5
ISSN: 0001-6837

MESH Headings:

Peat Preparation
Angiogenic Activity
Retinopathy

Published with permission from Acta Poloniae Pharmaceutica - Drug Research