The Effect of Peat Preparation on the Release of Histamine from Basophils of Atopic Asthmatics

Abstract:

Antigen-induced basophil histamine release (BHR) is an in vitro model of the immediate-type allergic reaction. We studied the influence of an immunologically active peat preparation (TPP) on BHR induced with specific antigen or Con A. The highest concentration of TPP enhanced antigen-induced BHR, and lower concentrations reduced it. Surprisingly, a similar effect was observed with the placebo, which suggests that immunologically inactive components of both preparations may be responsible for the modulatory activity.

Author:

Kowalski, M. L. Kuzminska, B. Rozniecki, J.

Abbreviated Journal Title: Pneum Alerg Pol
Date of Publication: 1992
Journal Volume: 60
Page Numbers: 58 through 63
Country of Publication: Poland
Language of Article: Polish
Issue/Part/Supplement: 11-12
ISSN:

MESH Headings:

Peat Preparation
Basophil Histamine Release
Immediate-Type Allergic Reaction

Published with permission from Pneumonologia i Alergologia Polska